Dr Thomas “Trey” Westbrook
Dr. Thomas Westbrook (“Trey”) is an associate professor of Molecular & Human Genetics at Baylor College of Medicine and an Era of Hope Scholar in Breast Cancer Research. Westbrook received his Ph.D. from the University of Rochester School of Medicine for his work on the role of DNA viruses in cancer. He continued his passion for cancer research and genetics during postdoctoral training with Dr. Stephen Elledge at Harvard Medical School. During this time, Dr. Westbrook developed new technologies for genetic screens in mammalian systems that have become widely used in the scientific community to solve problems of human disease.
In 2007, Westbrook joined the faculty at Baylor College of Medicine where his research team continues to develop new genetic technologies. Dr. Westbrook’s team has leveraged these genetic tools to discover the genes controlling breast cancer growth and response to treatment. Dr. Westbrook’s team has identified unexpected gene circuits that contribute to triple-negative breast cancer (TNBC). With creative genetic approaches, his team explores how these cancer genes confer unique vulnerabilities in cancer cells. With partners in academia and pharma, Westbrook and colleagues have translated these vulnerabilities into new therapies for breast cancer patients currently in clinical trials.
Dr. Westbrook’s innovations have been widely recognized and published in journals including Science, Nature, and Cell. For his contributions to science and commitment to cancer research, Dr. Westbrook has received numerous awards including the TAMEST Edith & Peter O’Donnell Award in Medicine and the Michael E. DeBakey Award for Excellence in Research.