Professor Adrian Harris is Cancer Research UK’s Professor of Medical Oncology at the University of Oxford and directs the Cancer Research UK Molecular Oncology Laboratories at the Weatherall Institute of Molecular Medicine. He is a Consultant Medical Oncologist and a Professorial Fellow of St Hugh’s College Oxford. He is Chair of the Translational Research Committee of the CRUK Oxford Cancer Centre as well as Chair of the Science Strategy Committee for Breast Cancer Now. He is also Editor in Chief of the British Journal of Cancer. His major laboratory interests involve the role of hypoxia in breast tumour biology, and tumour angiogenesis, the metabolic response to hypoxia, microRNAs induced by hypoxia and hypoxia-induced cell death. He has conducted many predictive and prognostic studies and early exploratory phase trials in new drug development and molecular pathology to translate laboratory findings to clinical relevance and development of new agents. In the clinical department over 20 Phase I and II trials are run and current trials include new drugs blocking multiple pathways of angiogenesis, and targeting HER2 with toxins. Specific emphasis is on classification of tumours by functional imaging, molecular profiles, and pharmacodynamic endpoints.