Professor Steffi Oesterreich
Dr. Oesterreich was recruited to the University of Pittsburgh in August 2010 as Professor with Tenure in the Department of Pharmacology and Chemical Biology, and as Director of Education in the Women’s Cancer Research Center, a collaboration between the University of Pittsburgh Cancer Institute and Magee-Womens Research Institute. Her laboratory focuses on mechanisms of endocrine resistance in breast cancer. Through the use of diverse cell and molecular biology approaches, mouse models, and clinical specimens, her group aims to identify the genetic and epigenetic changes that cause resistance to anti-estrogen therapies and that can be targeted to prevent, overcome or reverse resistance. Over the last five years, she has developed a research program in invasive lobular breast cancer (ILC), the second most common histological subtype of breast cancer. These studies focus on ER action in ILC, and on drivers of metastases.
She has authored over 120 peer-reviewed scientific articles in the area of breast cancer, serves on editorial boards for Cancer Research and Hormones and Cancer, and functions as Associate Editor for Breast Cancer Research. Dr Oesterreich was recently elected as Susan G Komen Scholar, joining a selective group of leading national and international breast cancer experts. She recently finished chairing the Tumor Cell Biology Study Section at the NIH, and will be chairing the next Gordon Research Conference on Hormones and Cancer. Dr Oesterreich and her husband Dr. Lee, also a breast cancer researcher at UPMC HCC, and their 2 daughters are happy in Pittsburgh, and proudly present a 4 person-Pitt-household, with both daughters currently attending the University of Pittsburgh.