Dr Charlotte Coles
Dr Charlotte Coles is a Reader in Breast Radiation Research at the Cancer Research UK Cambridge Centre, UK. Her research aims are to provide breast cancer patients with the best chance of cure with least side effects by personalising radiation techniques based on risk of recurrence. She is Chief Investigator of 4 clinical trials with linked translational research:
1. IMPORT LOW (n=2018): randomised trial (RCT) testing intensity modulated radiotherapy (IMRT) and partial breast radiotherapy in patients at low risk of recurrence – in follow up
2. IMPORT HIGH (n=2621): RCT testing dose-escalated IMRT for patients at higher risk of recurrence – in follow up
3. PRIMETIME (n=2200): Post-operative avoidance of radiotherapy in minimal risk women: patient selection using biomarkers – open
4. NEO-RT (n=50): pre-operative breast IMRT in patients receiving neo-adjuvant hormonal treatment – in set up
Dr Coles is also Chair of the NCRI Breast Clinical Studies Early Disease Subgroup and Editor-in-Chief of Clinical Oncology journal.